Laurent Brochard Selected Research

Hydrocortisone (Cortisol)

10/2020	Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
11/2012	Takotsubo syndrome secondary to adrenal adenocarcinoma: cortisol as a possible culprit.

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Laurent Brochard Research Topics

Disease

53	Respiratory Insufficiency (Respiratory Failure) 05/2024 - 08/2002
50	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 03/2024 - 07/2002
35	Critical Illness (Critically Ill) 03/2024 - 03/2003
18	Lung Injury 11/2023 - 09/2002
17	Chronic Obstructive Pulmonary Disease (COPD) 01/2024 - 04/2003
17	Acute Lung Injury 01/2023 - 07/2002
15	Hypoxia (Hypoxemia) 09/2023 - 06/2009
13	COVID-19 01/2024 - 01/2020
11	Infections 01/2022 - 07/2002
9	Ventilator-Induced Lung Injury 03/2024 - 02/2013
8	Pneumonia (Pneumonitis) 12/2023 - 01/2003
8	Pulmonary Edema 01/2018 - 09/2002
7	Shock 10/2020 - 11/2003
7	Patient-Ventilator Asynchrony 09/2016 - 10/2006
7	Acute Kidney Injury (Acute Renal Failure) 10/2013 - 04/2004
6	Sepsis (Septicemia) 12/2023 - 03/2005
6	Hypercapnia 02/2017 - 02/2008
5	Cross Infection (Nosocomial Infection) 04/2016 - 02/2002
4	Dyspnea (Shortness of Breath) 01/2022 - 11/2005
4	Delirium 01/2020 - 02/2010
4	Body Weight (Weight, Body) 01/2018 - 04/2002
3	Acidosis 09/2023 - 02/2017
3	Inflammation (Inflammations) 01/2022 - 03/2006
3	Fatigue 01/2022 - 11/2011
3	Muscle Weakness 01/2017 - 10/2009
3	Neoplasms (Cancer) 12/2016 - 09/2002
3	Human Influenza (Influenza) 05/2016 - 05/2011
3	Lung Diseases (Lung Disease) 02/2016 - 08/2010
3	Renal Insufficiency (Renal Failure) 12/2012 - 12/2003
3	Fibrosis (Cirrhosis) 12/2004 - 05/2003
2	Atrophy 02/2024 - 10/2020
2	Brain Injuries (Brain Injury) 12/2023 - 07/2002
2	Respiratory Acidosis 01/2022 - 01/2017
2	Septic Shock (Toxic Shock Syndrome) 01/2022 - 05/2012
2	Pulmonary Atelectasis 12/2020 - 12/2006
2	Edema (Dropsy) 01/2020 - 09/2002
2	Out-of-Hospital Cardiac Arrest 01/2018 - 06/2006
2	Ventilator-Associated Pneumonia 07/2014 - 11/2005
2	Paralysis (Palsy) 05/2013 - 09/2006
2	Obstructive Lung Diseases (Obstructive Lung Disease) 10/2012 - 08/2010
2	Pulmonary Hypertension 09/2010 - 03/2008
2	Acute Chest Syndrome 08/2010 - 03/2008
2	Sickle Cell Anemia (Hemoglobin S Disease) 08/2010 - 12/2003
2	Pain (Aches) 08/2010 - 12/2003
2	Bacterial Pneumonia 08/2004 - 09/2002
2	Neutropenia 01/2003 - 09/2002
1	Wounds and Injuries (Trauma) 12/2023
1	Heart Diseases (Heart Disease) 12/2023
1	Cough 01/2023

Drug/Important Bio-Agent (IBA)

30	Oxygen (Dioxygen)IBA 03/2024 - 01/2002
7	Surface-Active Agents (Surfactants)IBA 01/2022 - 03/2006
5	Carbon DioxideIBA 01/2024 - 02/2006
5	GasesIBA 11/2023 - 11/2005
5	Biomarkers (Surrogate Marker)IBA 01/2023 - 03/2006
5	Colloids (Colloid)IBA 09/2012 - 12/2004
5	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 05/2003 - 09/2002
4	Lidocaine (Xylocaine)FDA LinkGeneric 01/2022 - 09/2002
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2018
3	Hypnotics and Sedatives (Sedatives)IBA 01/2020 - 11/2015
3	HeliumIBA 01/2017 - 01/2010
3	Anti-Bacterial Agents (Antibiotics)IBA 05/2016 - 01/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2006 - 09/2002
2	Neuromuscular Blocking AgentsIBA 09/2023 - 07/2021
2	Fentanyl (Sublimaze)FDA LinkGeneric 09/2023 - 09/2006
2	Bronchodilator Agents (Bronchodilators)IBA 08/2023 - 10/2011
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2020 - 05/2011
2	Hydrocortisone (Cortisol)FDA LinkGeneric 10/2020 - 11/2012
2	Proteins (Proteins, Gene)FDA Link 03/2019 - 09/2002
2	Pancreatic Elastase (Elastase)IBA 01/2018 - 08/2004
2	AerosolsIBA 02/2016 - 10/2011
2	NitrogenIBA 06/2015 - 01/2011
2	SteroidsIBA 03/2014 - 05/2011
2	Bleomycin (Blenoxane)FDA LinkGeneric 08/2004 - 05/2003
2	EndotoxinsIBA 08/2004 - 01/2003
2	Peroxidase (Myeloperoxidase)IBA 05/2003 - 09/2002
2	Interleukin-1beta (Interleukin 1 beta)IBA 01/2003 - 09/2002
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2003 - 09/2002
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2023
1	Albuterol (Salbutamol)FDA LinkGeneric 08/2023
1	Claudin-5IBA 01/2023

Therapy/Procedure

74	Artificial Respiration (Mechanical Ventilation) 05/2024 - 01/2002
40	Noninvasive Ventilation 01/2024 - 08/2002
28	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 03/2024 - 04/2002
25	Therapeutics 08/2023 - 09/2002
20	Mechanical Ventilators (Ventilator) 01/2024 - 04/2004
13	Critical Care (Surgical Intensive Care) 01/2022 - 03/2005
11	Extracorporeal Membrane Oxygenation 01/2024 - 02/2013
10	Cannula 08/2023 - 06/2015
7	Length of Stay 01/2022 - 04/2004
4	Humidifiers 01/2021 - 11/2005
3	Continuous Positive Airway Pressure 01/2024 - 11/2005
3	Catheters 03/2022 - 11/2003
3	Transplantation 09/2021 - 08/2011
3	Resuscitation 12/2013 - 12/2008
2	Deep Sedation 01/2022 - 09/2006
2	Tracheostomy 01/2020 - 05/2003
2	Interactive Ventilatory Support 03/2016 - 11/2011
2	Drug Therapy (Chemotherapy) 01/2003 - 09/2002
1	Anesthesia 01/2024
1	Nebulizers and Vaporizers (Inhaler) 08/2023